Everyone wants white teeth, but not so much when that color appears in spots or blotches. Technically known as white lesions, white spots can develop on your teeth due a range of factors from diet to ingesting fluoride as a child. Common causes include: Fluorosis – Though fluoride is essential for strengthening teeth and preventing decay, too much fluoride in developing teeth can lead to low amounts of calcification, which causes spots of softer enamel and ...